9 Best Ergonomic Mice in 2020 – For Wrist Pain and Carpal Tunnel

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best ergonomic mice
A lot of people who spend copious amounts of time tinkering with their computers are complaining about pain in their fingers and wrists. Many of them are also having back problems, but this is not today’s topic. The problems with CTS and tendonitis are mostly due to repetitive tasks done all day long while using a “normie” mouse. Hence today’s topic is about the best ergonomic mouse, i.e. a piece of gear specially designed for people spending countless hours on their computers doing repetitive tasks. We know, it sounds sad and redundant, but that’s how life is.

Using a well-designed ergonomic mouse will make all the difference in the world in regard to both comfort and productivity, whether we’re talking about a wireless mouse or a wired variety. Obviously, if you want to enhance the experience even more in terms of comfort for your fingers and wrists, you should also get yourself an ergonomic keyboard. And speaking of ergonomics, a lot of people with CTS (carpal tunnel syndrome) swear on vertical mice, but we’ll talk about that a little bit later in the show, right after a short commercial break.

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Why Use an Ergonomic Mouse

First, here’s the TL;DR version of why use an ergonomic mouse in the first place: as we’ve already told you in the preamble of the article, using a regular mouse (even a trackball mouse by the way) when doing repetitive tasks all day while immersed in the matrix may result in various 21st century diseases, like repetitive strain injury or repetitive motion syndrome. However, you should know that these matrix-related issues are not actually new, as RMS and RSI go way back to the industrial revolution, when people started to act like robots on proto-assembly lines, doing the exact same moves thousands of times a day.

Today we are confronted with basically the same issue, sans the physical work of the industrial age, whether we’re playing GTA 5 and Candy Crush or doing PowerPoints all day: due to poorly designed (standard) mice, obsessive-compulsive “clickazoids” are suffering from tendonitis, carpal tunnel syndrome and various other things that affect their fingers, wrists and even shoulders. And that’s all due to the unnatural posture related to the unnatural task of staying in front of a screen all day and doing repetitive tasks.

A well designed ergonomic mouse (and keyboard) will not force your forearm, wrists and fingers in an unnatural posture, and that’s all there is to know at this point if you want to mitigate the risks of “job-related injuries”.

How to Choose the Best Ergonomic Mouse

There are hundreds of options out there, which means choosing the best ergonomic mouse may be quite difficult, especially if you’re a total noob. To make things simple, think along the lines of choosing the best gaming mouse, because yes, gaming mice are also ergonomically designed, since gamers are basically doing the same things as “clickazoids”(yes, we made this term up). So here it comes:


Size matters in all aspects of one’s life, i.e. the bigger the better, whether we’re talking about your car, smartphone or TV set. However, when it comes to ergonomic mice, this is a matter of personal preference, i.e. for best results, you’d have to take a test drive with different sized mice to see which one fits perfectly in your hand.


Grip is correlated with size, i.e. size and grip go together like peas and carrots, as in the ideal size of a given mouse depends on the type of one’s grip. And speaking of grip types, there’s the palm grip, which is the fastest and best for gamers (also comfortable), then the claw grip, and finally the fingertip grip. For more “intel” on “grip issues”, I’d recommend you to check out Razer’s mouse ergonomics guide as well as this YouTube video. As the general rule of thumb, palm-grip mice are best for people with RSI problems, as they put the least amount of stress on your forearm and wrist.

Wireless or Wired?

This is another factor that depends on one’s particular situation. Wireless mice are more expensive, and obviously require batteries (which makes them heavier), while some models may suffer from noticeable lag, an issue which can be particularly annoying in certain tasks. However, if you’re looking for convenience (no cables on your desk) and you don’t care about spending more money, a well-designed high-performance wireless mouse is hard to beat.


Again, this is a matter of personal preference. However, keep in mind that a heavier mouse requires more effort to move it around, hence on a long enough time-line, a heavier mouse may cause problems long-term, even if the difference in weight is negligible.


Since we live in the “current year”, adjustable DPI resolution is a must-have feature in an ergonomic mouse. Basically, adjustable DPI means you can adjust the cursor-speed to match your requirements/preference, as some tasks may require a low DPI setting, while others need a higher one. Adjustable DPI is very important if you’re a graphic artist, a gamer, a video editor or all of the above.

Ambidextrous Design

If you’re a “leftie”, you should know that most mice are designed for right-handed people; however, some of the best mice out there feature an ambidextrous design, while very few are specially designed for lefties. If you fall in the latter category, keep your eyes peeled before you buy.

Vertical Design

Here comes the mother lode of clickazoid ergonomics: vertically designed mice. The philosophy behind vertical design is that your hand forms an arch or a contour when it’s at rest. A vertically designed mouse will reproduce that contour, thus allowing you to keep your forearm in a neutral posture, also known as the handshake position. This posture promotes both accuracy and comfort.

Now that we’ve cleared things up, let’s see the contenders for the best ergonomic mouse.

9 Best Ergonomic Mice

Logitech MX Ergo Wireless Trackball Mouse

Amazing Duo

logitech mx ergo wireless trackball mouse
The Logitech MX Ergo is a very interesting beast, as it plays on both ends of the specter, i.e. it’s both an ergonomic mouse and a trackball, with an emphasis on the latter. Some say that the MX Ergo makes for the best thumb operated trackball in the known universe, due to its specially designed tilt-feature, which makes it supremely comfy (can tilt twenty degrees). To make a long story short, if you’re looking for a thumb-operated trackball, which by the way is smooth, relatively small and easy to use, the MX Ergo should rank high on your shopping list.

Logitech also provides a rechargeable battery in the retail package, which lasts for months in a row (more than a year according to the company), and on top of that, the MX Ergo can connect to your PC via Bluetooth or by using Logitech’s unifying dongle. Bottom line: in the land of regular mice, the Logitech MX Ergo is the king (of trackballs).


  • the trackball is very accurate
  • supremely comfortable
  • dual connectivity (Bluetooth & dongle)
  • high-quality scroll wheel
  • 8 customizable buttons
  • excellent build quality
  • comes with magnetic metal stand
  • 18 months autonomy on a single charge
  • cross computer control via Logitech Flow

  • kind of heavy at 263 g
  • right-handed version only

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Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

The Best Ergonomic Vertical Mouse

anker 2 4g wireless vertical ergonomic optical mouse
If you’re looking for a dirt cheap vertical ergonomic mouse, the Anker 2.4 G checks all the boxes: for a ridiculously low price, you’ll get a vertical design, 5 programmable buttons, adjustable DPI resolution (800/1200/1600) and wireless technology. To make a long story short, the Anker 2.4 G delivers amazing value for money, and that’s pretty obvious if you consider the fact that this mouse is a best-seller since its debut (6 years ago!).

To tell you the truth, this is arguably the best vertical ergo-mouse in the ~$20 range, and you can take that to the bank. The vertical design minimizes wrist movement, which is associated with carpal tunnel syndrome and RSI, and despite its affordable price, this mouse doesn’t look or feels cheap. Bottom line: if you’re looking for an entry-level vertical ergo-mouse, the Anker 2.4 G is very easy to recommend.


  • great ergonomics
  • amazing value for money
  • looks and feels high-quality
  • multiple tracking options
  • works on glass
  • comes with next/previous buttons for browsing
  • features physical switch button for DPI settings
  • shuts down automatically to preserve battery

  • weirdly placed next/previous buttons
  • not as precise as high-end mice
  • kind of slippery

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CORSAIR Glaive Pro

The Best Ergonomic Gaming Mouse

corsair glaive pro
Corsair is a legendary brand for gamers, and their latest Glaive Pro makes for an update of sorts of their already-popular GLAIVE RGB. Okay, the truth is that this is a true-blue gaming mouse (built for comfort, mind you), but as we’ve already told you in the preamble, gaming mice are just as good as “ergonomic” ones, i.e. the Glaive Pro would definitely fit the bill if you’re looking for a supremely comfortable mouse which is also excellent for gaming.

Quality wise, the Glaive Pro is built like a rock, featuring a soft plastic finish, and feels awesome in hand. Some complain about this Corsair product as being to “plasticky” for gamers with exquisite tastes, but this is not an issue in the “real world”. As far as comfort and performance go, the Glaive Pro is here to deliver, and we must mention its unique interchangeable thumb-grip feature, which adds tremendous value to an already affordable mouse, as well as its 18.000 DPI sensor (adjustable DPI, of course).


  • excellent ergonomic mouse
  • 3 interchangeable magnetic thumb grips
  • 5 DPI settings
  • pixel-perfect precision
  • state of the art Pixart 3367 optical sensor
  • comes with Omron switches
  • supremely comfy
  • RGB, 6 customizable buttons
  • impeccable workmanship
  • good value for money
  • suited for both work and play

  • none really at this price

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Logitech MX Vertical Wireless Mouse

The Best Ergonomic Mouse for Wrist Pain

logitech mx vertical wireless mouse
Here comes another vertical wireless mouse, this time from Logitech, the granddaddy of PC peripherals. As usual, when it comes to a Logitech product, the MX Vertical Wireless mouse is over-engineered to the point of ridiculousness, but that’s hardly a surprise, at least for our regular readers. However, unlike the Anker Vertical Wireless ergonomic gizmo we’ve told you about previously, this Logitech is way more expensive, more than 4x actually, and the question is, is it worth it?

The short answer is yes. The long answer is Hell Yeah! Here’s why: as far as vertical mice go, the MX from Logitech is precision crafted to reduce muscle pain by exactly ten percent, and that’s according to Logitech’s own in-house study. The point being that the MX Vertical uses a 57-degree angle to keep your hand in the handshake position, thus helping to reduce muscular strain and preventing forearm twisting.

Besides top-notch ergonomics, the MX Vertical comes with a strong 4000 DPI sensor and cross-computer control, i.e. you can copy-paste images, text or whatever over 3 computers (simultaneous navigation) using Logitech’s Flow software. And the thing is, you can literally use this mouse on 3 computers in the same time, Mac or Windows machines, as the MX Vertical comes with three ways to connect: Bluetooth, USB Type C (cable included in the retail bundle) or Logitech’s USB Unifying Receiver.


  • smooth performing ergonomic mouse
  • looks awesome
  • 4000 DPI sensor
  • customizable DPI range between 400 to 4000
  • cross computer control
  • designed to reduce wrist/hand strain
  • 3 ways to connect
  • rechargeable battery included in the package
  • up to 4 months autonomy on a single charge
  • great tactile feedback
  • phenomenal wireless performance via the Unifying Receiver
  • excellent option for workers on the move

  • kind of expensive
  • not really suited for gaming

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Razer Basilisk Gaming Mouse

The Best Ergonomic Wireless Mouse

razer basilisk
All work and no play makes Jack a dull boy, but here comes the improbably named Razer Basilisk (what’s in a name, right?), a gaming-centric product which can pass easily as an ergonomic mouse. Since we’re talking Razer, gaming and a weird name, it’s obvious that you’ll be in for a real treat, so check this out: the Basilisk boasts a laser-accurate (literally) 16,000 DPI optical sensor, customizable of course, along with no less than eight programmable buttons, gaming grade mechanical switches, Chroma RGB lightning and, last but not least, customizable scroll resistance.

The cherry on top is obviously the mouse’s excellent ergonomics, which make it suitable for playing in the best ergonomic mouse category. Oh, and we almost forgot: this baby is incredibly low-priced at the moment, so go get two of these bad boys while you still can!


  • ergonomic mouse with gaming-grade performance
  • very comfy
  • high precision 16,000 DPI sensor adjustable on-the-fly
  • features legendary PWM3389 sensor
  • gaming grade mechanical switches
  • programmable (8) buttons
  • cool minimalist design
  • RGB support
  • amazing value for money
  • excellent for both work and play

  • right-handed only version

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AmazonBasics Full-Size Ergonomic Wireless Mouse

Entry level Ergo-Mouse

amazonbasics full-size ergonomic wireless mouse
As its name suggests, the AmazonBasics ergonomic wireless mouse is an excellent choice if you’re looking for an entry-level full-sized device at an affordable price. For something in the “twenty-ish” range, you’ll get a well-designed and comfortable mouse, with fast scrolling and back/forth thumb buttons, which make internet-navigation a child’s play.

However, don’t expect miracles from the 1600 DPI sensor (boomer-era technology), but if you’re just “exploring” the ergonomic-niche or you’re game for a no-nonsense basic ergo-mouse, this mouse would make for the sensible option.


  • comfortable
  • ergonomic design
  • wireless via 2.4 GHz connection
  • fast scrolling
  • good value for money
  • works on Windows 7 and above

  • lacks precision
  • burns through batteries like crazy

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Logitech MX Master 3

Productivity BFF

logitech mx master 3
When it comes to computer peripherals, Logitech is king, and their latest MX Master 3 is arguably one of the best ergonomically designed mice in the universe. We’re only exaggerating a little bit for dramatic effect, but the truth is that the MX Master 3 is the master of ergonomic mice, making for a super-comfy gadget, boasting an electromagnetic (!) scroll wheel which allows precise/freewheeling motion. Everything’s at superlative with the MX Master 3, and its launching raised the bar in the industry, as this baby was specifically designed to enhance comfort and customizability (yes, that word really exists) for its target audience: designers, software developers and other PC-addicted professions.

Design-wise, the MX Master 3 is heavily inspired from the previous MX Master 2s generation, and that’s a good thing, because after all’s said and done, if something ain’t broke, don’t fix it. However, when it comes to “what’s under the hood”, well, here’s a different story, as the Master 3 comes with a redesigned scroll wheel made from machined steel (the electromagnetic thing dubbed MagSpeed), and one flick of this marvelous wheel can scroll through literally thousands of lines. The coders in the audience are smiling, we know, we can feel it, especially when they find out that the MX Master 3 will stay alive for 70 days on a single charge.


  • premium look and feel, highly customizable
  • supremely comfy, quiet and smooth scroll wheel
  • can control up to 3 machines simultaneously, including sharing text/files
  • dual connectivity via Bluetooth or 2.4 GHz dongle
  • the best scroll wheel in the “game” (made in Switzerland)

  • expensive

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ELECOM M-HT1DRBK Wireless Trackball Mouse

Good Choice for Carpal Tunnel

elecom m-ht1drbk wireless trackball mouse
Here comes another trackball beast, this time from Elecom, a wireless and ergonomically designed mouse which looks like it just landed on Amazon from a science fiction movie. To enforce the science-fiction comparison even more, the ELECOM M-HT1DRBK’s bright red track-ball looks just like HAL 9000, the sentient AI from 2001 A Space Odyssey. The point being, as far as mouse design goes, this baby looks and feels awesome. Another peculiar thing about this alien artifact is that it’s almost twice as big as a regular mouse, comes with eight buttons and its ergonomic design works quite well, i.e. the mouse is very comfy provided you don’t have tiny hands.

Another advantage of the ELECOM M-HT1DRBK is that it allows your wrist to maintain a neutral position, i.e. it helps with preventing carpal tunnel syndrome. Furthermore, the mouse is well built and rock solid, while its OMRON switches deliver an excellent tactile response.


  • excellent ergonomic design
  • accurate 1500 DPI sensor
  • high-quality trackball
  • cool design
  • solid build quality
  • 3 level DPI settings: 500-1000-1500
  • OMRON switches
  • smooth tracking
  • great for replacing MS Trackball Explorer
  • decent for MMORPG games
  • good value for money

  • no left-hand version

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Razer DeathAdder Elite

Jack of All Trades

Razer DeathAdder Elite
Finally, we close today’s piece with another excellently designed gaming mouse, which can pass the smell test at any time of the day if you’re looking for comfort, precision and affordability in one cool package. Razer is known for making some of the best gaming mice in the world, and the DeathAdder Elite is no exception, due to its high-end 16,000 DPI laser sensor and 1000 Hz polling rate. There’s no fast-moving hand this baby can’t handle, due to its custom/in-house made 5G sensor which tracks at 450 IPS.

Tech talk aside, the DeathAdder elite is ergonomically contoured and its classic shape and size make it ideal for small-handed folks looking for a “petite” ergo-mouse. In case you were wondering, these are the “metrics” (pun intended): 5.00 x 2.76 x 1.73 inches.


  • ergonomically designed
  • very comfy
  • 7 customizable buttons
  • high-end laser sensor
  • 16,000 DPI, amazing gaming performance
  • Razer-modified OMRON switches
  • impeccable build quality
  • high-quality side-buttons
  • accommodates virtually all grip-types

  • none really at this price-point

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